Key West Luxury Homes for a Spa Break

We selected the 466 homes worth renting in this location

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Adults

Age 13+

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Children

Age 1 to 12

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Infants

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Home spotlights in Key West

Shellstone Magic

Shellstone Magic

  • 16 guests

  • 8 bedrooms

Key Haven, Key West

This modern coastal retreat is all about laid-back luxury and sun-soaked living. With an ultra-sleek design, spacious interiors, and a private pool, it’s made for unwinding in style.

The Tidal Flow

The Tidal Flow

  • 12 guests

  • 4 bedrooms

Key Haven, Key West

Set beside the water in a quiet gated community, this Key West retreat is all breezy days and golden-hour swims. Coastal tones and soft natural light bring a sense of calm throughout, while outside, the private pool, dock, and fenced garden make it easy to unwind.

Lakeside Getaway

Lakeside Getaway

  • 18 guests

  • 9 bedrooms

Barrier Island, Fort Lauderdale

This dream Fort Lauderdale retreat is perfect for families and large groups. Set right on the Mayan Lake, it offers three private suites – each with their own living space, kitchen, and dining area.

Marina Nights

Marina Nights

  • 14 guests

  • 6 bedrooms

Key Haven, Key West

This home has bagged itself a great location in a gated community, less than a mile from ever-popular Key West. With a private pool, alfresco dining area, and fire pit, outdoor living is easy here.

We selected the top 3% holiday homes in Key West Luxury Homes for a Spa Break

Explore the 466 most perfect homes in our collection

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Most popular homes in Key West

Waterway Dream

Waterway Dream

  • 2 guests

  • 1 bedrooms

Central Beach, Fort Lauderdale

Blushing Peach

Blushing Peach

  • 10 guests

  • 5 bedrooms

Nurmi Isles, Fort Lauderdale

Key Lime Delight

Key Lime Delight

  • 16 guests

  • 5 bedrooms

Key Haven, Key West

The Pearl of Key West

The Pearl of Key West

  • 16 guests

  • 6 bedrooms

Key Haven, Key West

A Drop of Sunlight

A Drop of Sunlight

  • 18 guests

  • 7 bedrooms

Nurmi Isles, Fort Lauderdale

Endless Ocean

Endless Ocean

  • 8 guests

  • 4 bedrooms

Birch Park Finger Streets, Fort Lauderdale

Waterfront Magic

Waterfront Magic

  • 16 guests

  • 7 bedrooms

Marathon, Monroe County

Peaceful Waterway

Peaceful Waterway

  • 2 guests

  • 1 bedrooms

Coral Ridge, Fort Lauderdale

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Frequently asked questions

Similar destinations

Take a look at all of our luxury homes for a spa break in Key West, Monroe County, Florida, United States. Book your relaxing trip away today and leave your troubles at the door, because thanks to our meticulous Home Critics, you won't have any once you're inside. All of our homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Whether your stay is short or extended, stay in one of our luxury homes for a spa break in Key West, Monroe County, Florida, United States and get the rest you deserve.

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