Key West Luxury Homes for a Spa Break

We selected the 466 homes worth renting in this location

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Home spotlights in Key West

Shellstone Magic

Shellstone Magic

  • 16 guests

  • 8 bedrooms

Key Haven, Key West

This modern coastal retreat is all about laid-back luxury and sun-soaked living. With an ultra-sleek design, spacious interiors, and a private pool, it’s made for unwinding in style.

Waterfront Pearl

Waterfront Pearl

  • 16 guests

  • 8 bedrooms

Key Haven, Key West

Nestled within an exclusive gated community less than a mile from vibrant Key West, this stunning home offers a truly exceptional experience. With breathtaking waterfront views and a private pool, it's the perfect sanctuary to relax and unwind.

Lakeside Getaway

Lakeside Getaway

  • 18 guests

  • 9 bedrooms

Barrier Island, Fort Lauderdale

This dream Fort Lauderdale retreat is perfect for families and large groups. Set right on the Mayan Lake, it offers three private suites – each with their own living space, kitchen, and dining area.

Keys to Paradise

Keys to Paradise

  • 14 guests

  • 6 bedrooms

Key Haven, Key West

If you’re seeking an authentic Florida Keys experience, then look no further. This home is located within a gated community, less than a mile from popular Key West.

We selected the top 3% holiday homes in Key West Luxury Homes for a Spa Break

Explore the 466 most perfect homes in our collection

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Most popular homes in Key West

Waterway Dream

Waterway Dream

  • 2 guests

  • 1 bedrooms

Central Beach, Fort Lauderdale

Who Is Love to You

Who Is Love to You

  • 6 guests

  • 3 bedrooms

Coral Ridge, Fort Lauderdale

The Theodore

The Theodore

  • 16 guests

  • 6 bedrooms

Key Haven, Key West

Dream Escape

Dream Escape

  • 14 guests

  • 6 bedrooms

Key Haven, Key West

Endless Ocean

Endless Ocean

  • 8 guests

  • 4 bedrooms

Birch Park Finger Streets, Fort Lauderdale

Golden Acres

Golden Acres

  • 8 guests

  • 3 bedrooms

Rural Estates, Collier County

Waterfront Magic

Waterfront Magic

  • 16 guests

  • 7 bedrooms

Marathon, Monroe County

Peaceful Waterway

Peaceful Waterway

  • 2 guests

  • 1 bedrooms

Coral Ridge, Fort Lauderdale

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Similar destinations

Take a look at all of our luxury homes for a spa break in Key West, Monroe County, Florida, United States. Book your relaxing trip away today and leave your troubles at the door, because thanks to our meticulous Home Critics, you won't have any once you're inside. All of our homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Whether your stay is short or extended, stay in one of our luxury homes for a spa break in Key West, Monroe County, Florida, United States and get the rest you deserve.

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