Plum guide offers a handpicked selection of the most unique homes in Isle of Palms, SC, U.S.. Our homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Book a short or extended stay and secure the most unique home in Isle of Palms, SC, U.S. for your next getaway. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.