Book a stay in one of the best homes in Syracuse

We selected the 124 homes worth renting in this location

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Home spotlights in Syracuse

Colours of The Desert

Colours of The Desert

  • 2 guests

  • 1 bedrooms

Syracuse, Sicily

Contemporary living meets Sicilian charm in this traditional home. Located in the historic area of Ortigia, you'll be surrounded by ancient streets contrasting this stylishly modern apartment.

Aretusa Sunset

Aretusa Sunset

  • 6 guests

  • 3 bedrooms

Syracuse, Sicily

Located in Piazza Duomo, this apartment is an idyllic spot to enjoy Isola di Ortigia and Syracuse. From here, you can reach the marina’s waterfront restaurants, Fonte Aretusa, Chiesa di Santa Lucia alla Badia and Cala Rossa Beach – just keep in mind this is a very small rocky beach.

Isola Bliss

Isola Bliss

  • 14 guests

  • 5 bedrooms

Syracuse, Sicily

If you’re visiting Syracuse as a large group, these five suites in Isola di Ortigia are just the spot for a family and friends retreat. With four suites offering individual kitchenettes and dining areas, there’s plenty of space and privacy here.

Vigliena View

Vigliena View

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

This beautiful apartment is in a stunning position in the historic centre of Ortigia, a UNESCO World Heritage Site. It’s in front of Forte Vigliena, an ancient Bourbon-era fortress.


We selected the top 3% holiday homes in Syracuse

Explore the 124 most perfect homes in our collection

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Most popular homes in Syracuse

The Lady of Ortigia

The Lady of Ortigia

  • 8 guests

  • 4 bedrooms

Syracuse, Sicily

Sicilian Blush

Sicilian Blush

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

Ortigia Elegance

Ortigia Elegance

  • 4 guests

  • 1 bedrooms

Syracuse, Sicily

Pink Oleanders

Pink Oleanders

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

In the Heart of Ortigia

In the Heart of Ortigia

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

Ortigia Blush

Ortigia Blush

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

Sea Of Joy

Sea Of Joy

  • 6 guests

  • 3 bedrooms

Syracuse, Sicily

Raw Materials

Raw Materials

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

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