Book Luxury Vacation Rentals in Santiago do Cacém

Award-winning homes from £98

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Home spotlights in Santiago do Cacém

Sunkissed Delight

Sunkissed Delight

  • 14 guests

  • 8 bedrooms

Santiago do Cacém, Setubal

This stunning home is the perfect escape. It’s tucked away in Santiago do Cacém in a peaceful spot – it was originally home to the friars of the Order of Santiago.

Casa Zen

Casa Zen

  • 12 guests

  • 5 bedrooms

São Francisco da Serra, Santiago do Cacém

Nestled between the wild Atlantic shore and the majestic Serra de Grândola, the village of Melides is often described as Alentejo´s best-kept secret. And perched high in the surrounding hills, this home is perfectly poised to reveal the magic that makes this region so special.

Casa Roriz

Casa Roriz

  • 8 guests

  • 4 bedrooms

Santo André, Santiago do Cacém

This modern villa offers a stylish haven for those seeking a relaxing Portuguese escape. Situated in the heart of quiet countryside, the home is within easy access to the stunning beaches of the Alentejo Coast – however, you will need a car to get around.

The Light of the World

The Light of the World

  • 21 guests

  • 9 bedrooms

São Francisco da Serra, Santiago do Cacém

Anyone in search of a fuss-free retreat on the beautiful coast of Comporta will love this home. Secluded, rustic and simple – it’s the ideal setting to switch off and embrace the magic of the great outdoors.


We selected the top 3% holiday homes in Santiago do Cacém Vacation Rentals

Explore the 1528 most perfect homes in our collection

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Most popular homes in Santiago do Cacém

Fairies of the Forest

Fairies of the Forest

  • 6 guests

  • 3 bedrooms

Santa Margarida da Serra, Grândola

Distant Blue

Distant Blue

  • 10 guests

  • 5 bedrooms

Cercal do Alentejo, Santiago do Cacém

Beachy Boho

Beachy Boho

  • 4 guests

  • 2 bedrooms

Comporta, Alcácer do Sal

Casa da Comporta

Casa da Comporta

  • 8 guests

  • 4 bedrooms

Comporta, Alcácer do Sal

Cabanas da Comporta

Cabanas da Comporta

  • 6 guests

  • 3 bedrooms

Carvalhal, Grândola

A Touch of Tranquility

A Touch of Tranquility

  • 6 guests

  • 3 bedrooms

Castelo, Sesimbra

Forever Peace

Forever Peace

  • 10 guests

  • 5 bedrooms

Grândola, Setubal

The Spice of Carvalhal

The Spice of Carvalhal

  • 6 guests

  • 3 bedrooms

Lagoa Formosa, Brejo da Carregueira

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Frequently asked questions

Take a look at our collection of luxury Vacation Rentals in Santiago do Cacém. All of the homes you'll find on Plum Guide come fully furnished with all linen, the best-equipped kitchens, and essential bathroom toiletries included. Each home is systematically reviewed before becoming part of our collection, so you can book your stay with total confidence. And if you require any assistance in finding the perfect Santiago do Cacém Vacation Rentals for you, get in touch with our team of friendly experts, on hand to help with whatever you need.

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