Book Luxury Villas in Santiago do Cacém

We selected the 258 homes worth renting in this location

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Home spotlights in Santiago do Cacém

Emerald & Crimson

Emerald & Crimson

  • 14 guests

  • 7 bedrooms

Grândola, Setubal

Echoing the traditional red tiles of Portuguese architecture, this impressive villa features a stunning crimson façade that's especially captivating thanks to its abundantly vivacious, contrasting green surroundings. Encompassed by verdant fauna, sprawling gardens and an emerald-green infinity pool, we might just define this home as bliss itself.

By Land or Sea

By Land or Sea

  • 10 guests

  • 5 bedrooms

Tavira, Algarve

Providing a powerful juxtaposition with its lush, green surroundings, this distinct white villa combines luxury with relaxation to bring you a little slice of serenity on the Algarve. Take a step inside and you'll find an open space, perfect for entertaining guests or spending precious time with loved ones.

A Portuguese Tale

A Portuguese Tale

  • 10 guests

  • 6 bedrooms

Tunes, Silves

Surrounded by orange and almond trees and with a commanding position atop a hill, this home in the Algarve provides an escape high on tranquillity. You can enjoy flexible sleeping arrangements here thanks to the outbuilding – great if you're travelling with staff or teenagers – while the home has plenty of space to relax indoors and out.

Heaven is a Place

Heaven is a Place

  • 10 guests

  • 4 bedrooms

Comporta, Alcácer do Sal

In the picturesque heart of Comporta, this home welcomes you to slow down and enjoy the magic of outdoor living. From the heated pool and the stunning views to the thoughtfully designed rooms, every detail has been considered to inspire ease and relaxation.


We selected the top 3% holiday homes in Santiago do Cacém Villas

Explore the 258 most perfect homes in our collection

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Most popular homes in Santiago do Cacém

Distant Blue

Distant Blue

  • 10 guests

  • 5 bedrooms

Cercal do Alentejo, Santiago do Cacém

The Flower District

The Flower District

  • 14 guests

  • 7 bedrooms

Comporta, Alcácer do Sal

Wild West Coast

Wild West Coast

  • 6 guests

  • 3 bedrooms

Carvalhal, Grândola

The Sunset Muse

The Sunset Muse

  • 7 guests

  • 4 bedrooms

Santa Bárbara de Nexe, Algarve

Beachcomber Blues

Beachcomber Blues

  • 6 guests

  • 3 bedrooms

Comporta, Alcácer do Sal

Casa da Comporta

Casa da Comporta

  • 8 guests

  • 4 bedrooms

Comporta, Alcácer do Sal

Woven in Magic

Woven in Magic

  • 6 guests

  • 3 bedrooms

Comporta, Alcácer do Sal

Olive Oyl

Olive Oyl

  • 4 guests

  • 2 bedrooms

Tavira, Algarve

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Check upcoming rates & availability for Santiago do Cacém Villas


Frequently asked questions

Secure a luxury stay in one of the remarkable Villas in our Santiago do Cacém collection. Our quality and consistency is unmatched, with only the top 3% of homes making it onto our site. Our meticulous home experts test everything from shower pressure to a home's feel and atmosphere, so there really is no need to worry about a thing. Your chosen home is also guaranteed to be fully furnished, with an excellently-equipped kitchen, essential bathroom toiletries, and linens all included. Acquire the help of our friendly experts, on standby 24/7 and always eager to assist you in your hunt for the finest luxury Villa in the entirety of Santiago do Cacém.

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