Santo Spirito Luxury Houses

Award-winning homes from £98

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Home spotlights in Santo Spirito

Brick & Blush

Brick & Blush

  • 11 guests

  • 6 bedrooms

Montelupo Fiorentino, Florence

Drive around thirty minutes from Florence and towards the Tuscan Hills, where you’ll find this beautiful, restored villa. Surrounded by lush vegetation and breathtaking panoramic views, this home welcomes you with bold colours and plenty of heart.

Tuscan Harvest

Tuscan Harvest

  • 8 guests

  • 4 bedrooms

San Casciano In Val di Pesa, San Casciano in Val di Pesa

Located in the Chianti countryside, this tranquil villa is surrounded by forest-clad hills and overlooks a small lake. But don’t let the rural location fool you – you’re only 18 kilometres from Florence here.

A Poet's Paradise

A Poet's Paradise

  • 10 guests

  • 5 bedrooms

San Lorenzo, Florence

Surrounded by towering pines and sedate Cypress trees on the outskirts of Florence, this home – the poet Dante’s former residence – belongs in a league of its own. Characterised by its exquisitely decorated interiors, this historic abode wears its literary and artistic heritage on its sleeve – think hand-painted wall panels, multi-coloured glass chandeliers and terracotta tiled floors.

Florence and the Dream

Florence and the Dream

  • 5 guests

  • 3 bedrooms

San Lorenzo, Florence

Located in the historic district of San Lorenzo, this home is ideally situated to experience Florence, and immerse yourself in the medieval streets as you wander the area. Start each morning here with a cappuccino and frittata breakfast, enjoyed alfresco on the terrace area on warmer days.


We selected the top 3% holiday homes in Santo Spirito Houses

Explore the 96 most perfect homes in our collection

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Most popular homes in Santo Spirito

The Tuscan Table

The Tuscan Table

  • 14 guests

  • 5 bedrooms

Signa, Tuscany

Umberto Hills

Umberto Hills

  • 8 guests

  • 4 bedrooms

San Casciano in Val di Pesa, Florence

Tuscan Roots

Tuscan Roots

  • 2 guests

  • 1 bedrooms

San Casciano In Val di Pesa, San Casciano in Val di Pesa

Oliva Farmhouse

Oliva Farmhouse

  • 4 guests

  • 2 bedrooms

Montespertoli, Florence

An Ode To Wine

An Ode To Wine

  • 14 guests

  • 7 bedrooms

Bagnolo-Cantagallo, Impruneta

Love Can Build A Bridge

Love Can Build A Bridge

  • 8 guests

  • 3 bedrooms

San Giovanni, Florence

Viti House

Viti House

  • 9 guests

  • 5 bedrooms

Scandicci, Florence

Historic Hallways

Historic Hallways

  • 14 guests

  • 7 bedrooms

Impruneta, Florence

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Frequently asked questions

All Plum Guide houses in Santo Spirito, Florence, Tuscany, Italy have been tested and approved by our team of independent home critics. These meticulous beings inspect everything –from the convenience of each house’s location right down to the art on the walls– so what you see really is what you get. Worried about thin curtains? Accessibility? Maybe wifi speed is your biggest concern? Rest assured, we obsessively check each house in Santo Spirito, Florence, Tuscany, Italy before approving it, so you can book with peace of mind.

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