Book Luxury Vacation Rentals for May in Santo Spirito

We selected the 47 homes worth renting in this location

Who's coming along?

Adults

Age 13+

0

Children

Age 1 to 12

0

Infants

Under 1

0

Pets

An extra fee may apply

0

Home spotlights in Santo Spirito

The Basilica's Bell

The Basilica's Bell

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

It feels like you can almost touch the Church of Santo Spirito from the windows of this apartment – we love the vistas here. You also get glimpses of the cathedral from the living room (which also sleeps guests seven and eight on a sofa bed).

Arno View

Arno View

  • 6 guests

  • 2 bedrooms

Santo Spirito, Florence

This apartment in Florence boasts amazing views of the city and the Arno River. Housed in a 14th-century building, this elegant home, furnished with works by renowned local artists, offers a blend of historical charm and modern sophistication.

Fabulous In Florence

Fabulous In Florence

  • 7 guests

  • 3 bedrooms

San Frediano, Florence

If you've perfected your dream Florentine sightseeing list, then this apartment is the place for you. Located in the San Frediano neighborhood, just a stone's throw away from many of the city's most famous landmarks, it's a wonderful spot to kick back and relax between your adventures.

Palace on the Piazza

Palace on the Piazza

  • 7 guests

  • 4 bedrooms

San Frediano, Florence

How often do you get the chance to stay in a palace? On a darling little piazza?


We selected the top 3% holiday homes in Santo Spirito Vacation Rentals for May

Explore the 47 most perfect homes in our collection

View on map

Most popular homes in Santo Spirito

The Italian Way

The Italian Way

  • 12 guests

  • 4 bedrooms

Santo Spirito, Florence

Aria to a Bird

Aria to a Bird

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Ode to Santa Maria

Ode to Santa Maria

  • 4 guests

  • 1 bedrooms

District 1, Florence

Palazzo Pitti Retreat

Palazzo Pitti Retreat

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Palazzo Paradiso

Palazzo Paradiso

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

A Touch of Grace

A Touch of Grace

  • 5 guests

  • 2 bedrooms

Santo Spirito, Florence

Astride the Arno

Astride the Arno

  • 4 guests

  • 2 bedrooms

San Giovanni, Florence

Focal Length

Focal Length

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

View all

Check upcoming rates & availability for Santo Spirito Vacation Rentals for May


Frequently asked questions

Discover our exclusive collection of the finest Vacation Rentals for May that Santo Spirito, Florence, Tuscany, Italy has to offer, and mark the month with an unforgettable trip. At Plum Guide, we carefully select only the very best homes around, so you know that every rental is one to be proud of. Each home in our range comes fully furnished, with a well-equipped kitchen, all linen, and essential toiletries included. Our meticulous testing process ensures that no stone is left unturned, with everything from shower pressure and Wifi speed to a home's design aesthetic being thoroughly tested. Book a luxury Holiday Rental for May in Santo Spirito today, and see what all the fuss is about. If you need any guidance, call on our experts, ready night and day to help you find your ideal home.

Search our collection