Syracuse Weekend House Rentals

We selected the 24 homes worth renting in this location

Home spotlights in Syracuse

Spirit of Ortigia

Spirit of Ortigia

  • 2 guests

  • 1 bedrooms

Syracuse, Sicily

You’ll find this apartment in the heart of Ortigia, the historical centre of Syracuse. As an open-plan space, it’s perfect for a couple keen to base themselves within easy reach of the city’s main attractions.

Vigliena Vigil

Vigliena Vigil

  • 4 guests

  • 2 bedrooms

Siracusa, Italy

Located in the historic centre of Syracuse, this apartment is a stylish and unique place to stay. It overlooks the Forte Vigliena, an ancient fortress dating back to the Bourbon era – and it also boasts wonderful sea views.

Apollo View

Apollo View

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

This elegant apartment is perfect for a family, two couples, or a group of friends. We love the high ceilings and tall windows, which fill the space with light.

Isola Bliss

Isola Bliss

  • 14 guests

  • 5 bedrooms

Syracuse, Sicily

If you’re visiting Syracuse as a large group, these five suites in Isola di Ortigia are just the spot for a family and friends retreat. With four suites offering individual kitchenettes and dining areas, there’s plenty of space and privacy here.


We selected the top 3% holiday homes in Syracuse Weekend House Rentals

Explore the 24 most perfect homes in our collection

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Most popular homes in Syracuse

Ortigia Blush

Ortigia Blush

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

In the Heart of Ortigia

In the Heart of Ortigia

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

The Lady of Ortigia

The Lady of Ortigia

  • 8 guests

  • 4 bedrooms

Syracuse, Sicily

Aretusa Sunset

Aretusa Sunset

  • 6 guests

  • 3 bedrooms

Syracuse, Sicily

Neptune's View

Neptune's View

  • 8 guests

  • 4 bedrooms

Syracuse, Sicily

Shades of Ortigia

Shades of Ortigia

  • 6 guests

  • 3 bedrooms

Syracuse, Sicily

Vigliena View

Vigliena View

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

Sicilian Blush

Sicilian Blush

  • 4 guests

  • 2 bedrooms

Syracuse, Sicily

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Frequently asked questions

Looking to book a holiday rental for the weekend in Syracuse, Sicily, Italy? You've come to the right place: we’re the official selection of the world’s best homes. Our collection of weekend rentals in Syracuse, Sicily, Italy come fully furnished with well-equipped kitchens, toiletries in bathrooms & all linen included. We obsessively check each home for you, so you can book with peace of mind. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.

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