Book Luxury Vacation Rentals in Santo António

Award-winning homes from £98

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Home spotlights in Santo António

Black Leather

Black Leather

  • 4 guests

  • 2 bedrooms

Bairro Alto, Margueira

This slick, multi-level apartment sits in cool and central Príncipe Real. Inside is characterful, warm, and welcoming.

Bom Bocado

Bom Bocado

  • 2 guests

  • 1 bedrooms

Arroios, Lisbon

Boasting a lively, multicultural atmosphere and plenty of parks, art galleries and eateries, Anjos is widely considered to be the trendiest neighbourhood in Lisbon. It’s also very well-connected, just fifteen minutes from the historic centre by public transport yet tucked away from the tourist hustle and bustle.

The Eucalyptus

The Eucalyptus

  • 4 guests

  • 1 bedrooms

Santo António, Lisbon

Stay in one of Lisbon's most prestigious avenues, Avenida da Liberdade, in this stylish apartment with a 24-hour concierge and shared indoor pool. Though the kitchen is a little sparse, it’s got all the essentials for quick breakfasts and at-home lunches.

Serene Serendipity

Serene Serendipity

  • 4 guests

  • 2 bedrooms

Santo António, Lisbon

Taking inspiration from Indonesia’s beautiful landscapes, this bright apartment in Lisbon’s central Santo Antonio neighbourhood feels like a beachy paradise overlooking the city’s rooftops. Gaze out onto scenic views from the living area’s macrame hanging chair while a record serenades you, or, gather together for a celebratory Portuguese feast around the palm-framed dining table as the sun dips through the large windows.


We selected the top 3% holiday homes in Santo António Vacation Rentals

Explore the 81 most perfect homes in our collection

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Most popular homes in Santo António

Sofa Wine

Sofa Wine

  • 4 guests

  • 1 bedrooms

Santo António, Lisbon

Palms & Zebras

Palms & Zebras

  • 2 guests

  • 1 bedrooms

Príncipe Real, Lisbon

Linda Avenida

Linda Avenida

  • 4 guests

  • 1 bedrooms

Santa Maria Maior, Lisbon

Nova Inspirada

Nova Inspirada

  • 6 guests

  • 3 bedrooms

Santo António, Lisbon

Flower Square

Flower Square

  • 4 guests

  • 2 bedrooms

Santo António, Lisbon

Lisbon Retreat

Lisbon Retreat

  • 2 guests

  • 1 bedrooms

Príncipe Real, Lisbon

The Yellow Tram

The Yellow Tram

  • 4 guests

  • 2 bedrooms

Misericórdia, Lisbon

Green Library

Green Library

  • 3 guests

  • 2 bedrooms

Príncipe Real, Lisbon

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Frequently asked questions

Take a look at our collection of luxury Vacation Rentals in Santo António, Lisbon, Portugal. All of the homes you'll find on Plum Guide come fully furnished with all linen, the best-equipped kitchens, and essential bathroom toiletries included. Each home is systematically reviewed before becoming part of our collection, so you can book your stay with total confidence. And if you require any assistance in finding the perfect Santo António Vacation Rentals for you, get in touch with our team of friendly experts, on hand to help with whatever you need.

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