San Diego County Five Bedroom Homes

We selected the 434 homes worth renting in this location

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Age 13+

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Age 1 to 12

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Home spotlights in San Diego County

California King

California King

  • 16 guests

  • 6 bedrooms

Elfin Forest, San Diego County

Nestled into the San Diego hillside, this sprawling home is something nearer to an estate. We’ll let you decide whether you’d like to enjoy the impeccable views over the valley from the bedroom, dining table, pool or tennis court.

Golden State

Golden State

  • 8 guests

  • 5 bedrooms

Ventura, California

Dreaming of sunny California? This luxury beach house captures the best that the Golden State has to offer.

The Garden Cactus

The Garden Cactus

  • 12 guests

  • 5 bedrooms

La Quinta, Riverside County

This home, crowned by a backdrop of mountains, is ideal for group getaways to La Quinta. Surrounded by the Anza-Borrego Desert State Park, the famous Coachella Valley, and the iconic Joshua Tree, it's a gateway to hiking trails and golf courses.

Rock Bottom

Rock Bottom

  • 10 guests

  • 5 bedrooms

Mission Beach, San Diego

You won’t get much closer to the beach than this San Diego villa, nudged up to the golden sands of South Mission. With panoramic sea views, you’re in a prime position for watching the sunset over the North Pacific Ocean from the beachfront terrace or balcony.


We selected the top 3% holiday homes in San Diego County Five Bedroom Homes

Explore the 434 most perfect homes in our collection

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Most popular homes in San Diego County

Hummingbird Dawn

Hummingbird Dawn

  • 8 guests

  • 5 bedrooms

Encinitas, San Diego County

Mojave Rhythm

Mojave Rhythm

  • 10 guests

  • 5 bedrooms

Joshua Tree, San Bernardino County

The Ocean's Smile

The Ocean's Smile

  • 10 guests

  • 5 bedrooms

La Jolla Shores, San Diego

Mountain Pose

Mountain Pose

  • 12 guests

  • 6 bedrooms

Yucca Valley, San Bernardino County

Desert Nomad

Desert Nomad

  • 12 guests

  • 5 bedrooms

Joshua Tree, San Bernardino County

Pearly Whites

Pearly Whites

  • 12 guests

  • 6 bedrooms

La Jolla Shores, San Diego

The Crystal Pillow

The Crystal Pillow

  • 16 guests

  • 6 bedrooms

Carlsbad Village, Carlsbad

The Good King

The Good King

  • 22 guests

  • 10 bedrooms

Riverside County, California

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Frequently asked questions

Spacious 5 bedroom homes in San Diego County, California, United States. Plum Guide’s homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Book today and enjoy a short or extended stay in the best 5 bedroom homes that San Diego County, California, United States has to offer. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.

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