San Diego County Five Bedroom Homes

We selected the 400 homes worth renting in this location

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Home spotlights in San Diego County

California King

California King

  • 16 guests

  • 6 bedrooms

Elfin Forest, San Diego County

Nestled into the San Diego hillside, this sprawling home is something nearer to an estate. We’ll let you decide whether you’d like to enjoy the impeccable views over the valley from the bedroom, dining table, pool or tennis court.

Mountain Pose

Mountain Pose

  • 12 guests

  • 6 bedrooms

Yucca Valley, San Bernardino County

Set in acres and acres of untamed desert landscape, it doesn’t get much more serene than this palatial Joshua Tree villa. The surreal landscape of boulders and cacti is illuminated with custom lighting at night so you can admire it during a moonlight soak in the hot tub, or an evening dip in the sunken cowboy tub as the desert sky is speckled with stars.

Straight From the Vine

Straight From the Vine

  • 18 guests

  • 8 bedrooms

Riverside County, California

Hidden away among vineyards and rolling hillsides in southern California, this is an estate that's as picturesque as they come. The outside area has been designed to appreciate the gorgeous views and you can admire these from the comfort of the infinity pool, in the hot tub or sat around the barbecue and fire pit area.

Dolphin Bay

Dolphin Bay

  • 11 guests

  • 5 bedrooms

La Jolla Shores, San Diego

Waking up to ocean vistas is a scene you'll never tire of at this immaculate beachfront home, placed just steps from the golden shores of La Jolla - San Diego's most desirable seafront neighbourhood. Bright, light, and breezy with vaulted ceilings and cool, wooden floors – this is Californian-style living at its finest.


We selected the top 3% holiday homes in San Diego County Five Bedroom Homes

Explore the 400 most perfect homes in our collection

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Most popular homes in San Diego County

Blue Star

Blue Star

  • 8 guests

  • 5 bedrooms

Palacio Del Mar, San Diego

The Dawn Wall

The Dawn Wall

  • 10 guests

  • 5 bedrooms

San Clemente, Orange County

The Ocean's Smile

The Ocean's Smile

  • 10 guests

  • 5 bedrooms

La Jolla Shores, San Diego

Sunset Sonata

Sunset Sonata

  • 10 guests

  • 5 bedrooms

Yucca Valley, San Bernardino County

Famous Faces

Famous Faces

  • 10 guests

  • 5 bedrooms

Ruth Hardy Park, Palm Springs

Hummingbird Dawn

Hummingbird Dawn

  • 8 guests

  • 5 bedrooms

Encinitas, San Diego County

Casa Molino

Casa Molino

  • 12 guests

  • 5 bedrooms

Rancho Santa Fe, San Diego County

The Good King

The Good King

  • 22 guests

  • 10 bedrooms

Riverside County, California

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Frequently asked questions

Spacious 5 bedroom homes in San Diego County, California, United States. Plum Guide’s homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Book today and enjoy a short or extended stay in the best 5 bedroom homes that San Diego County, California, United States has to offer. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.

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