San Diego Five Bedroom Homes

We selected the 480 homes worth renting in this location

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Home spotlights in San Diego

The Ocean Glimmer

The Ocean Glimmer

  • 10 guests

  • 5 bedrooms

Encinitas, San Diego County

With its views across Moonlight Beach, luxurious roof terrace and Scandinavian design, this is the kind of home that captivates you from the moment of arrival. And once inside, you might find it hard to leave.

Palm Springs Gem

Palm Springs Gem

  • 8 guests

  • 5 bedrooms

Historic Tennis Club, Palm Springs

Palm trees, cacti, and the San Jacinto Mountains as your backdrop – it doesn’t get more Palm Springs than this. Full of mid-century charm with all the modern comforts, it’s close to downtown but tucked away in a quiet spot.

Zenith Valley

Zenith Valley

  • 12 guests

  • 6 bedrooms

Yucca Valley, San Bernardino County

Visiting Joshua Tree is one thing, but seeing a big portion from the comfort of your bath is another. If the latter sounds like a bucket list goal, then Zenith Valley is for you.

Si, Señorita

Si, Señorita

  • 16 guests

  • 13 bedrooms

Elfin Forest, San Diego County

Hidden in the rocky hills of Escondido, this Californian home opens its doors onto a large and luxurious playground. Like a warm embrace, the interiors reflect traditional Spanish style with a fun twist.

We selected the top 3% holiday homes in San Diego Five Bedroom Homes

Explore the 480 most perfect homes in our collection

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Most popular homes in San Diego

Pacific Spirit

Pacific Spirit

  • 12 guests

  • 6 bedrooms

Lower Hermosa, San Diego

The Good King

The Good King

  • 22 guests

  • 10 bedrooms

Riverside County, California

Rockin' in the Roundabout

Rockin' in the Roundabout

  • 10 guests

  • 5 bedrooms

Village of La Jolla, San Diego

Desert Spirit

Desert Spirit

  • 14 guests

  • 6 bedrooms

Racquet Club West, Palm Springs

Golden State

Golden State

  • 8 guests

  • 5 bedrooms

Ventura, California

California King

California King

  • 16 guests

  • 6 bedrooms

Elfin Forest, San Diego County

The Paintbrush

The Paintbrush

  • 13 guests

  • 6 bedrooms

Coronado, California

Eye of the Desert

Eye of the Desert

  • 6 guests

  • 5 bedrooms

San Bernardino County, California

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Frequently asked questions

Spacious 5 bedroom homes in San Diego, San Diego County, California, United States. Plum Guide’s homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Book today and enjoy a short or extended stay in the best 5 bedroom homes that San Diego, San Diego County, California, United States has to offer. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.

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