Book Luxury Airbnb Alternatives in Santo Spirito

We selected the 74 homes worth renting in this location

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Home spotlights in Santo Spirito

San Frediano Flair

San Frediano Flair

  • 4 guests

  • 2 bedrooms

San Frediano, Florence

If you want to explore Florence on foot, then head for this sleek apartment in the San Frediano district. A short stroll away from many of the city's best-loved attractions, it's the perfect place to begin your adventures.

Cocoa & Lime

Cocoa & Lime

  • 5 guests

  • 3 bedrooms

San Frediano, Florence

A laidback and welcoming apartment in Florence’s cool San Frediano district, this place makes you feel at home as soon as you step through the door. The timber ceiling beams in the living space add a rustic charm and we loved the contrasting lime green and mocha brown colour scheme.

The Heart of San Frediano

The Heart of San Frediano

  • 6 guests

  • 2 bedrooms

Santo Spirito, Florence

Minutes south of the River Arno, this functional Florentine apartment is a solid option for families looking to explore the storied city. While it lacks a traditional living area – the sofa bed is found in an alcove beside the bathroom – there's still plenty of space to get settled, including a dining area for socialising and a good size master bedroom.

The Basilica's Bell

The Basilica's Bell

  • 8 guests

  • 3 bedrooms

Santo Spirito, Florence

It feels like you can almost touch the Church of Santo Spirito from the windows of this apartment – we love the vistas here. You also get glimpses of the cathedral from the living room (which also sleeps guests seven and eight on a sofa bed).


We selected the top 3% holiday homes in Santo Spirito Airbnb Alternatives

Explore the 74 most perfect homes in our collection

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Most popular homes in Santo Spirito

A Touch of Grace

A Touch of Grace

  • 5 guests

  • 2 bedrooms

Santo Spirito, Florence

The Raffaella Rose

The Raffaella Rose

  • 3 guests

  • 1 bedrooms

San Frediano, Florence

What a Pitti

What a Pitti

  • 4 guests

  • 2 bedrooms

Santo Spirito, Florence

Palazzo in the City

Palazzo in the City

  • 10 guests

  • 5 bedrooms

Santo Spirito, Florence

Soft Sunrise

Soft Sunrise

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Grazie Mille

Grazie Mille

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

Astronomical Observatory View

Astronomical Observatory View

  • 6 guests

  • 2 bedrooms

San Frediano, Florence

Terracotta & White Wood

Terracotta & White Wood

  • 6 guests

  • 3 bedrooms

Santo Spirito, Florence

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Frequently asked questions

Airbnb is a shot in the dark. We meticulously vet all our homes in Santo Spirito to ensure you won’t waste your precious holiday. Every home you'll find on Plum Guide comes fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Before being accepted into our collection, each home much pass a meticulous vetting process, culminating in a personal home visit from an independent Home Critic. Rent one of Plum Guide's luxury Santo Spirito Airbnb Alternatives, and enjoy a long or short stay to remember. Should you need any assistance with your booking, our friendly team of experts will be on hand to guide you through the process.

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