Book Luxury Airbnb Alternatives in Santo Spirito

We selected the 80 homes worth renting in this location

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Home spotlights in Santo Spirito

Brick & Arch

Brick & Arch

  • 4 guests

  • 1 bedrooms

Santo Spirito, Florence

From its exposed brick walls to its beamed ceilings and arched windows, this rustic-meets-modern apartment is a slice of Florentine traditionalism, given a swish 21st-century sparkle. The open-plan main room is the home’s sociable heart, with plump sofas congregated around a large screen for cosy movie nights over a bottle of Italian wine and an elegant dining space that beckons home-cooked feasts when you’re not out sampling the local trattorias.

A Divine Vista

A Divine Vista

  • 2 guests

  • 1 bedrooms

San Frediano, Florence

If you're after a comfortable and convenient stay, this one's for you. And, while size may not be this studio's strong point, it has lots going for it, including views over the rooftops of Florence and a compact kitchenette for prepping light bites.

The Heart of San Frediano

The Heart of San Frediano

  • 6 guests

  • 2 bedrooms

Santo Spirito, Florence

Minutes south of the River Arno, this functional Florentine apartment is a solid option for families looking to explore the storied city. While it lacks a traditional living area – the sofa bed is found in an alcove beside the bathroom – there's still plenty of space to get settled, including a dining area for socialising and a good size master bedroom.

A Quiet Home

A Quiet Home

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Behind the grand stone walls of a 15th-century palace, this renaissance-painted apartment offers a beautiful base for discovering Florence. Found in the heart of the Oltrarno district – known for its local artisans and slower pace – it’s a peaceful retreat after a day exploring the city.


We selected the top 3% holiday homes in Santo Spirito Airbnb Alternatives

Explore the 80 most perfect homes in our collection

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Most popular homes in Santo Spirito

Between the Bridges

Between the Bridges

  • 6 guests

  • 3 bedrooms

San Giovanni, Florence

Aria to a Bird

Aria to a Bird

  • 2 guests

  • 1 bedrooms

Santo Spirito, Florence

Pitti Pad

Pitti Pad

  • 8 guests

  • 4 bedrooms

Santo Spirito, Florence

Palazzo in the City

Palazzo in the City

  • 10 guests

  • 5 bedrooms

Santo Spirito, Florence

Alberata Grande

Alberata Grande

  • 7 guests

  • 3 bedrooms

Santo Spirito, Florence

Fabulous In Florence

Fabulous In Florence

  • 7 guests

  • 3 bedrooms

San Frediano, Florence

A Touch of Grace

A Touch of Grace

  • 5 guests

  • 2 bedrooms

Santo Spirito, Florence

The Raffaella Rose

The Raffaella Rose

  • 3 guests

  • 1 bedrooms

San Frediano, Florence

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Frequently asked questions

Airbnb is a shot in the dark. We meticulously vet all our homes in Santo Spirito to ensure you won’t waste your precious holiday. Every home you'll find on Plum Guide comes fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Before being accepted into our collection, each home much pass a meticulous vetting process, culminating in a personal home visit from an independent Home Critic. Rent one of Plum Guide's luxury Santo Spirito Airbnb Alternatives, and enjoy a long or short stay to remember. Should you need any assistance with your booking, our friendly team of experts will be on hand to guide you through the process.

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