San Diego Unique Homes

We selected the 119 homes worth renting in this location

Home spotlights in San Diego

The Paintbrush

The Paintbrush

  • 13 guests

  • 6 bedrooms

Coronado, California

Spread across two apartments, this two-storey Coronado Island home is ideal for two families travelling together, or a multi-generational reunion. The living spaces and kitchens on both floors let you spend some time with those closest to you, while the garden and alfresco area allow you to come together and enjoy the sun.

The Ocean at our Soles

The Ocean at our Soles

  • 9 guests

  • 4 bedrooms

Mission Beach, San Diego

Facing out across the Pacific Ocean, this three-storey beachside San Diego home offers plenty of vantage points to enjoy incredible views. The three top-floor bedrooms all offer great views and easy access to the balconies, while the ground-floor bedroom and bathroom, accessible only during summer, are ideal for teenagers who might prefer some space.

Hummingbird Dawn

Hummingbird Dawn

  • 8 guests

  • 5 bedrooms

Encinitas, San Diego County

Sophisticated yet comfortable, this resort-style home is sure to impress. It’s in the city of Encinitas, close to the beach but far enough away from the hustle and bustle to make for a relaxing base.

Pacific Spirit

Pacific Spirit

  • 12 guests

  • 6 bedrooms

Lower Hermosa, San Diego

With direct access to Windansea Beach, this home makes the perfect setting for a laid-back coastal escape. You’ll be welcomed by beautiful views across La Jolla, a heated swimming pool and plenty of space to relax both inside and out.


We selected the top 3% holiday homes in San Diego Unique Homes

Explore the 119 most perfect homes in our collection

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Most popular homes in San Diego

Charming Gaslamp Retreat

Charming Gaslamp Retreat

  • 8 guests

  • 2 bedrooms

East Village, San Diego

Pacific Pinnacle

Pacific Pinnacle

  • 4 guests

  • 2 bedrooms

Beach Barber Tract, San Diego

Golden State Retreat

Golden State Retreat

  • 12 guests

  • 4 bedrooms

La Mesa, California

Heaven's Corner

Heaven's Corner

  • 8 guests

  • 4 bedrooms

Lower Hermosa, San Diego

Vista Vista

Vista Vista

  • 16 guests

  • 4 bedrooms

Mission Hills, San Diego

Radiant Coastal Retreat

Radiant Coastal Retreat

  • 4 guests

  • 2 bedrooms

Beach Barber Tract, San Diego

Ocean Breeze Bliss

Ocean Breeze Bliss

  • 6 guests

  • 3 bedrooms

Beach Barber Tract, San Diego

The Coastal Haven

The Coastal Haven

  • 2 guests

  • 1 bedrooms

Beach Barber Tract, San Diego

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Frequently asked questions

Plum guide offers a handpicked selection of the most unique homes in San Diego, San Diego County, California, United States. Our homes come fully furnished with the best-equipped kitchens, essential bathroom toiletries and all linen included. Book a short or extended stay and secure the most unique home in San Diego, San Diego County, California, United States for your next getaway. Our friendly team of Plum Experts are on-hand 24/7 should you need anything.

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